Authors L.E. Guimarães et al. review, Vaccines, adjuvants and autoimmunity, examine autoimmune diseases following vaccinations. “In this review of the literature, there is evidence of vaccine-induced autoimmunity and adjuvant-induced autoimmunity in both experimental models as well as human patients.”
Research focus is on adjuvants role in triggering disease.
“Scientific findings suggest that autoimmunity may be triggered by vaccine adjuvants, of which aluminum compounds (aluminum hydroxide and phosphate) have been the most studied and the most widely used.”
L.E. Guimarães et al. / Pharmacological Research 100 (2015) 190–209
“…Adjuvants and infectious agents may exert their immune-enhancing effects through various functional activities, encompassed by the adjuvant effect. These mechanisms are shared by different conditions triggered by adjuvants leading to the autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome).”
“…Recently a new syndrome was described: “Autoimmune/inflammatory syndrome induced by adjuvants” (ASIA). This embodies a spectrum of reactions, which are usually mild but may also be severe. These reactions are attributed to adjuvant stimulation, which can include chronic exposure to silicone, tetramethylpentadecane, pristane, aluminum, infectious components and other adjuvants. All of these environmental factors have been found to induce autoimmunity and inflammatory manifestations by themselves both in animal models and in humans.”